Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
MINCR
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
miR-223/ZEB1
Cancer name
Nasopharyngeal Carcinoma
Cancer site
Nasopharynx
Treatment type
Radiotherapy
Impact of wild-type ncRNA on radiotherapy resistance
down
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MINCR diminished NPC cell radiosensitivity by sponging miR-223, increasing ZEB1 and activating the AKT/PI3K.
Tissue resource
tissue biopsy from nasopharyngeal carcinoma patients
nasopharyngeal carcinoma cell lines CNE2
nasopharyngeal carcinoma cell lines CNE2R
Experiment
qRT-PCR,Western blot,Dual-Luciferase reporter assay
Institute
the First Hospital of Quanzhou Affiliated to Fujian Medical University
American Type Culture Collection
Country
China
USA
Continent
Asia
North American
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.