MINCR

ncRNA information

ncRNA name

MINCR

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

miR-223/ZEB1

Cancer information

Cancer name

Nasopharyngeal Carcinoma

Cancer site

Nasopharynx

Treatment information

Treatment type

Radiotherapy

Impact of wild-type ncRNA on radiotherapy resistance

down

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MINCR diminished NPC cell radiosensitivity by sponging miR-223, increasing ZEB1 and activating the AKT/PI3K.

Tissue resource

tissue biopsy from nasopharyngeal carcinoma patients

nasopharyngeal carcinoma cell lines CNE2

nasopharyngeal carcinoma cell lines CNE2R

Experiment

qRT-PCR,Western blot,Dual-Luciferase reporter assay


Institute

the First Hospital of Quanzhou Affiliated to Fujian Medical University

American Type Culture Collection

Country

China

USA

Continent

Asia

North American