hsa-miR-324-5p

ncRNA information

ncRNA name

hsa-miR-324-5p

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

FBXO11

Cancer information

Cancer name

Non-Small Cell Lung Cancer

Cancer site

Lung

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MiR-324-5p upregulation mediates, at least partially, the CDDP resistance by directly targeting FBXO11 signalling in LCa cells.

Tissue resource

human non-small cell lung cancer cell lines A549

human non-small cell lung cancer cell lines SPC-A1

Experiment

qRT-PCR,Western blot,Luciferase reporter assay


Institute

Shanghai Institute of Biochemistry and Cell Biology

Country

China

Continent

Asia