Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa_circ_0007841
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
Yes
Biomarker application
Prognosis
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Multiple Myeloma
Cancer site
Multiple Myeloma
Treatment type
Chemotherapy
Drug
Bortezomib
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Hsa_circ_0007841 is significantly upregulated in MM. It may be a novel biomarker for MM and its involvement in the progression of MM.
Tissue resource
bone marrow samples
normal human mononuclear cell lines THP-1
multiple myeloma cell lines KM3
multiple myeloma cell lines U266
multiple myeloma cell lines RPMI-8226
multiple myeloma drug-resistant cell lines KM3/BTZ
multiple myeloma drug-resistant cell lines U266/BTZ
multiple myeloma drug-resistant cell lines RPMI-8226/BTZ
Experiment
qRT-PCR
Institute
the Third Xiangya Hospital of Central South University
Central South University Xiangya School of Medicine
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.