hsa_circ_0007841

ncRNA information

ncRNA name

hsa_circ_0007841

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

Yes

Biomarker application

Prognosis

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Multiple Myeloma

Cancer site

Multiple Myeloma

Treatment information

Treatment type

Chemotherapy

Drug

Bortezomib

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Hsa_circ_0007841 is significantly upregulated in MM. It may be a novel biomarker for MM and its involvement in the progression of MM.

Tissue resource

bone marrow samples

normal human mononuclear cell lines THP-1

multiple myeloma cell lines KM3

multiple myeloma cell lines U266

multiple myeloma cell lines RPMI-8226

multiple myeloma drug-resistant cell lines KM3/BTZ

multiple myeloma drug-resistant cell lines U266/BTZ

multiple myeloma drug-resistant cell lines RPMI-8226/BTZ

Experiment

qRT-PCR


Institute

the Third Xiangya Hospital of Central South University

Central South University Xiangya School of Medicine

Country

China

Continent

Asia