SSTR5-AS1

ncRNA information

ncRNA name

SSTR5-AS1

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

NONO

Cancer information

Cancer name

Gallbladder Carcinoma

Cancer site

Gallbladder

Treatment information

Treatment type

Chemotherapy

Drug

Gemcitabine

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

NONO functions as the downstream effector of SSTR5-AS1 and is required for SSTR5-AS1 mediated gemcitabine resistance.

Tissue resource

gallbladder carcinoma tissues and adjacent tissues

gallbladder carcinoma cell lines GBC-SD

gallbladder carcinoma cell lines SGC-996

gallbladder carcinoma cell lines NOZ

Experiment

qRT-PCR,Western blot


Institute

Shanghai Jiaotong University Affiliated Sixth People's Hospital

the Cell Bank of Type Culture Collection of Chinese Academy of Sciences

Country

China

Continent

Asia