Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
SSTR5-AS1
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
NONO
Cancer name
Gallbladder Carcinoma
Cancer site
Gallbladder
Treatment type
Chemotherapy
Drug
Gemcitabine
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
NONO functions as the downstream effector of SSTR5-AS1 and is required for SSTR5-AS1 mediated gemcitabine resistance.
Tissue resource
gallbladder carcinoma tissues and adjacent tissues
gallbladder carcinoma cell lines GBC-SD
gallbladder carcinoma cell lines SGC-996
gallbladder carcinoma cell lines NOZ
Experiment
qRT-PCR,Western blot
Institute
Shanghai Jiaotong University Affiliated Sixth People's Hospital
the Cell Bank of Type Culture Collection of Chinese Academy of Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.