Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-762
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
ABR
Cancer name
Non-Small Cell Lung Cancer
Cancer site
Lung
Treatment type
Chemotherapy
Drug
Gefitinib
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MiR-762 inhibition and ABR restoration cotreatment in patients with recurrent EGFR mutant NSCLC to therapeutically combat the heterogeneity of EGFR-TKIs resistance mechanisms.
Tissue resource
non-small cell lung cancer tissue samples
human non-small cell lung cancer cell lines A549
human non-small cell lung cancer cell lines NCI-H820
human non-small cell lung cancer cell lines NCI-H2170
human non-small cell lung cancer cell lines NCI-H1650
human non-small cell lung cancer cell lines NCI-H1993
human non-small cell lung cancer cell lines NCI-H2126
human non-small cell lung cancer cell lines NCI-H1975
human non-small cell lung cancer cell lines NCI-H1299
human non-small cell lung cancer cell lines NCI-H1648
human non-small cell lung cancer cell lines NCI-H1703
human non-small cell lung cancer cell lines NCI-H2347
normal human lung epithelial cell lines NuLi-1
Experiment
qRT-PCR,Luciferase reporter assay
Institute
the Second Affiliated Hospital of Xi'an Medical University
American Type Culture Collection
American Type Culture Collection
American Type Culture Collection
American Type Culture Collection
American Type Culture Collection
American Type Culture Collection
American Type Culture Collection
American Type Culture Collection
American Type Culture Collection
American Type Culture Collection
American Type Culture Collection
American Type Culture Collection
Country
China
USA
Continent
Asia
North American
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.