CYTOR

ncRNA information

ncRNA name

CYTOR

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-125a-5p

Cancer information

Cancer name

Breast Cancer

Cancer site

Breast

Treatment information

Treatment type

Chemotherapy

Drug

Tamoxifen

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

The results of the present study demonstrated a pivotal role of CYTOR in mediating tamoxifen resistance in breast cancer.

Tissue resource

pairs of breast cancer and normal tissues

human breast cancer cell lines MCF7

pairs of tumor and normal tissues

human breast cancer cell lines MCF7

Experiment

qRT-PCR,Western blot,Dual-Luciferase reporter assay


Institute

the Cancer Hospital of China Medical University

American Type Culture Collection

Cancer Hospital of China Medical University

American Type Culture Collection

Country

China

USA

China

United States

Continent

Asia

North American

Asia

North Amercian