Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CYTOR
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-125a-5p
Cancer name
Breast Cancer
Cancer site
Breast
Treatment type
Chemotherapy
Drug
Tamoxifen
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
The results of the present study demonstrated a pivotal role of CYTOR in mediating tamoxifen resistance in breast cancer.
Tissue resource
pairs of breast cancer and normal tissues
human breast cancer cell lines MCF7
pairs of tumor and normal tissues
human breast cancer cell lines MCF7
Experiment
qRT-PCR,Western blot,Dual-Luciferase reporter assay
Institute
the Cancer Hospital of China Medical University
American Type Culture Collection
Cancer Hospital of China Medical University
American Type Culture Collection
Country
China
USA
China
United States
Continent
Asia
North American
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.