NORAD

ncRNA information

ncRNA name

NORAD

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-129-1-3p/SOX4

Cancer information

Cancer name

Non-Small Cell Lung Cancer

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

NORAD accelerates chemo-resistance of non-small-cell lung cancer via targeting at miR-129-1-3p/SOX4 axis

Tissue resource

non-small cell lung cancer tissues and adjacent normal tissues

normal human lung epithelium cell lines BEAS-2B

non-small cell lung cancer cell lines H446

non-small cell lung cancer cell lines A549

Experiment

None


Institute

Affiliated Xiaolan Hospital of Southern Medical University

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian