ncRNA name
NORAD
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-129-1-3p/SOX4
Cancer name
Non-Small Cell Lung Cancer
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
NORAD accelerates chemo-resistance of non-small-cell lung cancer via targeting at miR-129-1-3p/SOX4 axis
Tissue resource
non-small cell lung cancer tissues and adjacent normal tissues
normal human lung epithelium cell lines BEAS-2B
non-small cell lung cancer cell lines H446
non-small cell lung cancer cell lines A549
Experiment
None
Institute
Affiliated Xiaolan Hospital of Southern Medical University
American Type Culture Collection
Country
China
United States
Continent
Asia
North Amercian