CTRR-ncRNA

ncRNA information

ncRNA name

hsa-miR-200c-3p

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Neuropilin 1

Cancer information

Cancer name

Ovarian Cancer

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

Olaparib

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Down

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

31898520

Description

MiR-200c sensitizes Olaparib-resistant ovarian cancer cells by targeting Neuropilin 1

Tissue resource

human ovarian specimens

human ovarian cancer cell lines UWB1.289

human ovarian cancer cell lines UWB1.289+BRCA1

human ovarian cancer cell lines SKOV3

Experiment

None

Institute

Sapienza University of Rome

ATCC-LGC

Country

Italy

United Kingdom

Continent

European