Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-132-3p
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
TGF-Ī²1/Smad2/3
Cancer name
Oral Squamous Cell Carcinoma
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Down
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
miR-132 acts as a tumor suppressor and exerts a substantial role in inhibiting the proliferation, invasion, and enhanced the chemosensitivity to CDDP of OSCC via regulating TGF-Ī²1/Smad2/3 signals in vitro
Tissue resource
ovarian squamous cell carcinoma tissues and adjacent normal tissues
human ovarian squamous cell carcinoma cell lines SCC-9
human ovarian squamous cell carcinoma cell lines CAL-27
human oral keratinocyte cell lines HOK
Experiment
None
Institute
Department of Dental Center, the affiliated hospital of Qingdao University
American Type Culture Collection
BeNa Culture Collection
Country
China
United States
China
Continent
Asia
North Amercian
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.