hsa-miR-132-3p

ncRNA information

ncRNA name

hsa-miR-132-3p

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

TGF-Ī²1/Smad2/3

Cancer information

Cancer name

Oral Squamous Cell Carcinoma

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

miR-132 acts as a tumor suppressor and exerts a substantial role in inhibiting the proliferation, invasion, and enhanced the chemosensitivity to CDDP of OSCC via regulating TGF-Ī²1/Smad2/3 signals in vitro

Tissue resource

ovarian squamous cell carcinoma tissues and adjacent normal tissues

human ovarian squamous cell carcinoma cell lines SCC-9

human ovarian squamous cell carcinoma cell lines CAL-27

human oral keratinocyte cell lines HOK

Experiment

None


Institute

Department of Dental Center, the affiliated hospital of Qingdao University

American Type Culture Collection

BeNa Culture Collection

Country

China

United States

China

Continent

Asia

North Amercian

Asia