H19

ncRNA information

ncRNA name

H19

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Ovarian Cancer

Cancer site

Ovary

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Up

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

The overexpression of lncRNA in the OVCAR3 cells improved the cisplatin-resistance, and the inhibition of lncRNA H19 expression in OVCAR3/DDP cells eliminated the cisplatin resistance.

Tissue resource

human ovarian cancer cell lines OVCAR3

Experiment

Western blot


Institute

American Type Culture Collection

Country

USA

Continent

North American