MVIH

ncRNA information

ncRNA name

MVIH

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Non-Small Cell Lung Cancer

Cancer site

Lung

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Down

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Nedaplatin can reduce the expression of MVIH and reverse EMT process, thus reversing the drug resistance of cisplatin in non-small cell lung cancer cells.

Tissue resource

non-small cell lung cancer cell lines A549

non-small cell lung cancer cell lines H1650

non-small cell lung cancer cisplatin-resistant cell lines A549/DDP

non-small cell lung cancer cisplatin-resistant cell lines H1650/DDP

Experiment

None


Institute

Shanghai Cell Bank of the Chinese Academy of Sciences

Country

China

Continent

Asia