Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-202-5p
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
None
Biomarker application
Upstream regulatory factors
STAT5A
Downstream target
USP15/Caspase-6
Cancer name
Chronic Myeloid Leukemia
Cancer site
None
Treatment type
Chemotherapy
Drug
Imatinib
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Up
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
upregulation of miR-202-5p enhanced the resistance of CML cells to Imatinib by inhibiting cell apoptosis
Tissue resource
peripheral blood from healthy donors and chronic myeloid leukemia patients
human chronic myeloid leukemia cell lines KCL22
human chronic myeloid leukemia cell lines K562
Experiment
None
Institute
Department of Hematology of the Second Hospital of Hebei Medical University
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.