Exosome miR-567

ncRNA information

ncRNA name

Exosome miR-567

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Prognosis

Upstream regulatory factors

Not available

Downstream target

ATG5

Cancer information

Cancer name

Breast Cancer

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Trastuzumab

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer

Tissue resource

cancerous tissues from breast cancer

human HER-2-positive breast cancer cell lines SKBR-3

human HER-2-positive breast cancer cell lines BT474

Experiment

None


Institute

The First Affiliated Hospital of Zhengzhou University, The Second Affiliated Hospital of Chongqing Medical University, and Hainan General Hospital

American Type Culture Collection

Country

United States

Continent

North Amercian