LINC00461

ncRNA information

ncRNA name

LINC00461

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-593-5p/CCND1

Cancer information

Cancer name

Rectal Cancer

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Down

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Long noncoding RNA LINC00461 mediates cisplatin resistance of rectal cancer via miR-593-5p/CCND1 axis

Tissue resource

human rectal cancer cell lines SW1463

human rectal cancer cell lines HR8348

human rectal cancer cell lines SW837

normal human colorectal epithelial cell lines FHC

Experiment

None


Institute

Chinese Academy of Sciences

Country

China

Continent

Asia