ncRNA name
hsa-miR-153-3p
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Nrf-2
Cancer name
Esophageal Squamous Cell Carcinoma
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Down
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MicroRNA-153-3p regulates cell proliferation and cisplatin resistance via Nrf-2 in esophageal squamous cell carcinoma
Tissue resource
fresh esophageal squamous cell carcinoma samples along with paired adjacent nontumor tissue specimens
human esophageal squamous cell carcinoma cell lines Eca109
Experiment
None
Institute
Fourth Hospital of Hebei Medical University
Resource Center of the Peking Union Medical College Hospital of China
Country
China
China
Continent
Asia
Asia