Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
ROR
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Gastric Cancer
Cancer site
Stomach
Treatment type
Chemotherapy
Drug
Adriamycin/Vincristine
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
63
Male patients
31
Female patients
32
Age range and number
25(<60)+38(>=60)
PMID
Description
ROR expression promotes MRP1 expression and MDR of gastric cancer cells and is correlated with increased MDR and poor prognosis of patients with gastric cancer.
Tissue resource
gastric cancer tissues
human gastric cancer cell lines SGC-7901
human gastric cancer cell lines SGC-7901/ADR
human gastric cancer cell lines SGC-7901/VCR
human gastric cancer cell lines SGC-7SGC901/ADR+VCR
Experiment
qRT-PCR,Western blot
Institute
The Affiliated Hospital of Qingdao University
the Type Culture Collection of the Chinese Academy of Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.