POU6F2-AS2

ncRNA information

ncRNA name

POU6F2-AS2

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-377/BRD4

Cancer information

Cancer name

Colon Cancer

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

20-Fluorouracil

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Long non-coding RNA POU6F2-AS2 promotes cell proliferation and drug resistance in colon cancer by regulating miR-377/BRD4

Tissue resource

colon cancer and adjacent normal tissues

colon cancer cell lines HT-29

colon cancer cell lines HCT-116

colon cancer cell lines SW620

colon cancer cell lines OUMS23

normal colonic epithelial cell lines NCM460

Experiment

None


Institute

People's Hospital of Pudong

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian