DANCR

ncRNA information

ncRNA name

DANCR

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

IL-6/STAT3

Cancer information

Cancer name

Hepatocellular Carcinoma

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Sorafenib

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

LncRNA DANCR Promotes Sorafenib Resistance via Activation of IL-6/STAT3 Signaling in Hepatocellular Carcinoma Cells

Tissue resource

fresh clinical hepatocellular carcinoma and paired normal liver tissues

human embryonic kidney cell lines 293T

hepatocellular carcinoma cell lines Huh7

hepatocellular carcinoma cell lines Hep3B

Experiment

None


Institute

First People's Hospital of Tianmen City

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian