MALAT1

ncRNA information

ncRNA name

MALAT1

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-22-3p

Cancer information

Cancer name

Gastric Cancer

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Oxaliplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MALAT1 modulates ZFP91 to promote GC cells OXA resistance via sponging miR-22-3p

Tissue resource

gastric cancer tissues and normal tumor-adjacent tissuesZhangye People's Hospital Affiliated to Hexi University

normal cell lines GES-1

gastric cancer cell lines SGC-7901

gastric cancer cell lines BGC-823

gastric cancer oxaliplatin-resistant cell lines SGC-7901/OXA

gastric cancer oxaliplatin-resistant cell lines BCG-823/OXA

Experiment

None


Institute

RiboBio Co

Country

China

China

Continent

Asia

Asia