hsa-miR-451a

ncRNA information

ncRNA name

hsa-miR-451a

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

c-Myc

Cancer information

Cancer name

Lung Cancer

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

Doxorubicin

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MiR-451a attenuates doxorubicin resistance in lung cancer via suppressing epithelialmesenchymal transition (EMT) through targeting c-Myc

Tissue resource

human lung cancer cells lines A549

human lung cancer cells lines PC9

human lung cancer cells lines H1299

human lung cancer cells lines H460

Experiment

None


Institute

American Type Culture Collection

Country

United States

Continent

North Amercian