CCAT2

ncRNA information

ncRNA name

CCAT2

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-424

Cancer information

Cancer name

Glioma

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

None

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

lncRNA CCAT2 Enhanced Resistance of Glioma Cells Against Chemodrugs by Disturbing the Normal Function of miR-424

Tissue resource

neoplastic tissues and corresponding adjacent non-tumor tissues

normal human astrocyte cell lines NHA

human glioma cell lines U251

human glioma cell lines U87

human glioma cell lines A172

human glioma cell lines SHG44

Experiment

None


Institute

Shanghai Jiao Tong University Affiliated Sixth People's Hospital

cell culture bank of Chinese Academy of Sciences

Country

China

Switzerland

China

Continent

Asia

European

Asia