Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
TUG1
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-29b-3p
Cancer name
Ovarian Cancer
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Paclitaxel
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Long Noncoding RNA TUG1 Promotes Autophagy-Associated Paclitaxel Resistance by Sponging miR-29b-3p in Ovarian Cancer Cells
Tissue resource
Ovarian cancer samples and benign ovarian tumor samples
human ovarian cancer cell lines A2780
normal ovarian epithelial cell lines IOSE80
normal ovarian epithelial cell lines IOSE386
human embryonic kidney cell lines 293T
Experiment
None
Institute
Shanghai Pudong New Area People's Hospital
Canadian Ovarian Tissue Bank, British Columbia Cancer Research Centre
Chinese Academy of Sciences
Country
China
Canada
China
Continent
Asia
North Amercian
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.