AGAP2-AS1

ncRNA information

ncRNA name

AGAP2-AS1

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-497

Cancer information

Cancer name

Colorectal Cancer

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Gemcitabine

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

LncRNA AGAP2-AS1 augments cell viability and mobility, and confers gemcitabine resistance by inhibiting miR-497 in colorectal cancer

Tissue resource

human colorectal cancer tissues and matched adjacent normal tissues

colorectal cancer cell lines DLD-1

colorectal cancer cell lines SW480

colorectal cancer cell lines HT29

colorectal cancer cell lines CaCO2

colorectal cancer cell lines RKO

colorectal cancer cell lines HCT8

human embryonic kidney cell lines 293T

Experiment

None


Institute

First Hospital of Jilin University

Cell Bank of the Chinese Academy of Science

Country

China

China

Continent

Asia

Asia