Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
HANR
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-29b/ATG9A
Cancer name
Hepatocellular Carcinoma
Cancer site
qRT-PCR,Western blot,Dual-luciferase assay
Treatment type
Chemotherapy
Drug
Sorafenib
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
HANR enhanced sorafenib resistance by acting as an autophagy promoter by regulating miR-29b/ATG9A
Tissue resource
hepatocellular carcinoma samples and adjacent normal tissues
human hepatocellular carcinoma cell lines HepG2
human hepatocellular carcinoma cell lines Huh7
human embryonic kidney cell lines 293T
Experiment
None
Institute
Affiliated Hospital of Xuzhou Medical University
American Type Culture Collection
Country
China
United States
Continent
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.