HANR

ncRNA information

ncRNA name

HANR

Specific or universal ncRNAs

Specific ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-29b/ATG9A

Cancer information

Cancer name

Hepatocellular Carcinoma

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Sorafenib

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

HANR enhanced sorafenib resistance by acting as an autophagy promoter by regulating miR-29b/ATG9A

Tissue resource

hepatocellular carcinoma samples and adjacent normal tissues

human hepatocellular carcinoma cell lines HepG2

human hepatocellular carcinoma cell lines Huh7

human embryonic kidney cell lines 293T

Experiment

None


Institute

Affiliated Hospital of Xuzhou Medical University

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian