Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
DLEU1
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-381-3p/BIRC6
Cancer name
Nasopharyngeal Carcinoma
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Long Non-Coding RNA DLEU1 Up-Regulates BIRC6 Expression by Competitively Sponging miR-381-3p to Promote Cisplatin Resistance in Nasopharyngeal Carcinoma
Tissue resource
nasopharyngeal carcinoma tissues
human nasopharyngeal carcinoma cell lines 5-8F
human nasopharyngeal carcinoma cell lines 6-10B
human nasopharyngeal carcinoma cell lines C666-1
human nasopharyngeal carcinoma cell lines CNE1
human nasopharyngeal carcinoma cell lines CNE2
human nasopharyngeal carcinoma cell lines HNE-1
human nasopharyngeal carcinoma cell lines HONE-1
human nasopharyngeal carcinoma cell lines SUNE-1
Experiment
None
Institute
Zhuji People's Hospital
American Type Culture Collection
Country
China
United States
Continent
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.