Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
MALAT1
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
PI3K/AKT Pathway
Cancer name
Gastric Cancer
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
LncRNA MALAT1 Regulates the Cell Proliferation and Cisplatin Resistance in Gastric Cancer via PI3K/AKT Pathway
Tissue resource
pairs of gastric cancer tissues and paired nontumor tissues
human gastric cancer cell lines MKN45
human gastric cancer cell lines MKN28
human gastric cancer cell lines MGC-803
human gastric cancer cell lines HGC-27
human gastric cancer cell lines NCI-N87
human gastric cancer cell lines AGS
human gastric cancer cell lines GES-1
Experiment
None
Institute
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
American Type Culture Collection
Country
China
United States
Continent
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.