MALAT1

ncRNA information

ncRNA name

MALAT1

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

PI3K/AKT Pathway

Cancer information

Cancer name

Gastric Cancer

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

LncRNA MALAT1 Regulates the Cell Proliferation and Cisplatin Resistance in Gastric Cancer via PI3K/AKT Pathway

Tissue resource

pairs of gastric cancer tissues and paired nontumor tissues

human gastric cancer cell lines MKN45

human gastric cancer cell lines MKN28

human gastric cancer cell lines MGC-803

human gastric cancer cell lines HGC-27

human gastric cancer cell lines NCI-N87

human gastric cancer cell lines AGS

human gastric cancer cell lines GES-1

Experiment

None


Institute

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian