Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
HAS2-AS1
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Non-Small Cell Lung Cancer
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
Gefitinib
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
17
Male patients
13
Female patients
14(<65)+16(>=65)
Age range and number
Not available
PMID
Description
Long noncoding RNA HAS2-AS1 accelerates non-small cell lung cancer chemotherapy resistance by targeting LSD1/EphB3 pathway
Tissue resource
pairs of non-small cell lung cancer and their adjacent normal tissues
non-small cell lung cancer cell lines A549
non-small cell lung cancer cell lines H1299
non-small cell lung cancer cell lines SK-MES-1
non-small cell lung cancer cell lines H460
normal bronchial epithelial cell lines NHBE
Experiment
30
Institute
The Second Affiliated Hospital of Dalian Medical University
American Type Culture Collection
Country
China
United States
Continent
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.