Circ_ABCB10

ncRNA information

ncRNA name

Circ_ABCB10

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Let-7a-5p/DUSP7

Cancer information

Cancer name

Breast Cancer

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Circ-ABCB10 Contributes to Paclitaxel Resistance in Breast Cancer Through Let-7a-5p/DUSP7 Axis

Tissue resource

tissues from paclitaxel-sensitive or paclitaxel-resistant breast cancer patients

human breast epithelial cell line MCF-10A

human breast cancer cell lines MDA-MB-468

human breast cancer cell lines MDA-MB-453

human breast cancer cell lines MCF-7

human breast cancer cell lines MDA-MB-231

Experiment

None


Institute

Qingdao Chengyang People's Hospital

BeNa Culture Collection

Country

China

China

Continent

Asia

Asia