Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
Circ_ABCB10
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Let-7a-5p/DUSP7
Cancer name
Breast Cancer
Cancer site
qRT-PCR,Western blot,Dual-luciferase assay
Treatment type
Chemotherapy
Drug
Paclitaxel
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Circ-ABCB10 Contributes to Paclitaxel Resistance in Breast Cancer Through Let-7a-5p/DUSP7 Axis
Tissue resource
tissues from paclitaxel-sensitive or paclitaxel-resistant breast cancer patients
human breast epithelial cell line MCF-10A
human breast cancer cell lines MDA-MB-468
human breast cancer cell lines MDA-MB-453
human breast cancer cell lines MCF-7
human breast cancer cell lines MDA-MB-231
Experiment
None
Institute
Qingdao Chengyang People's Hospital
BeNa Culture Collection
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.