Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
NONHSAT141924
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Breast Cancer
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
Paclitaxel
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
LncRNA NONHSAT141924 promotes paclitaxel chemotherapy resistance through p-CREB/Bcl-2 apoptosis signaling pathway in breast cancer
Tissue resource
breast infiltrating ductal carcinoma tissues and their paired normal tissues
human breast cancer cell lines BT-549
human breast cancer cell lines MDA-MB-231
human breast cancer cell lines Hs-578T
human breast cancer cell lines ZR-75-30
human breast cancer cell lines T-47D
human breast cancer cell lines MCF-7
Experiment
None
Institute
First Affiliated Hospital of China Medical University
Cancer Institute of the First Affiliated Hospital
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.