Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
OIP5-AS1
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-137
Cancer name
Colon Cancer
Cancer site
qRT-PCR,Western blot,Dual-luciferase assay
Treatment type
Chemotherapy
Drug
Oxaliplatin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
silencing OIP5-AS1 reversed the resistance of CC cells to L-OHP by promoting the expression of miR-137
Tissue resource
colon cancer tissue specimens and corresponding tumor-adjacent tissue specimens
human colon cancer cell lines HCT116
human colon cancer cell lines LOVO
human colon cancer cell lines HT29
human colon cancer cell lines SW480
human normal colon epithelial cell lines FHC
Experiment
None
Institute
China-Japan Union Hospital of Jilin University
Nanjing Cobioer Biosciences Co., Ltd
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.