hsa-miR-454-3p

ncRNA information

ncRNA name

hsa-miR-454-3p

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

CYLD

Cancer information

Cancer name

Gastric Carcinoma

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Oxaliplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

miR-454 promotes survival and induces oxaliplatin resistance in gastric carcinoma cells by targeting CYLD

Tissue resource

human gastric cancer cell lines SGC-7901

Experiment

None


Institute

Cell Bank of the Guangzhou Institute of Biochemistry and Cell Biology

Country

China

Continent

Asia