Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CircMET
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-30-5p/snail/DPP4
Cancer name
Hepatocellular Carcinoma
Cancer site
qRT-PCR,Western blot,Dual-luciferase assay
Treatment type
Immunotherapy
Treatment name
Impact of wild-type ncRNA on resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
circMET is an onco-circRNA that induces HCC development and immune tolerance via the Snail/DPP4/CXCL10 axis
Tissue resource
Specimens obtained from the vicinity of the tumor margin were collected from patients with HCC
human HCC cell lines HCCLM3
human HCC cell lines Huh7
human HCC cell lines Hep3B
human HCC cell lines HepG2
Experiment
None
Institute
Fudan University Liver Cancer Institute
Liver Cancer Institute, Zhongshan Hospital
American Type Culture Collection
Country
China
China
United States
Continent
Asia
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.