NNT-AS1

ncRNA information

ncRNA name

NNT-AS1

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-1236-3p/ATG7

Cancer information

Cancer name

Lung Cancer

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

21

Male patients

10

Female patients

14(<=60)+17(>=60)

Age range and number

Not available

Research information

PMID

Description

Long Non-Coding RNA NNT-AS1 Contributes to Cisplatin Resistance via miR-1236-3p/ATG7 Axis in Lung Cancer Cells

Tissue resource

lung cancer tissues and paracancerous non-tumorous tissues

lung cancer cell lines H1299

lung cancer cell lines H23

lung cancer cell lines H522

lung cancer cell lines A549

human bronchial epithelioid cell lines 16-HBE

Experiment

31


Institute

First Affiliated Hospital of Medical College of Zhejiang University

BeNa Culture Collection

Country

China

China

Continent

Asia

Asia