Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
NNT-AS1
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-1236-3p/ATG7
Cancer name
Lung Cancer
Cancer site
qRT-PCR,Western blot,Dual-luciferase assay
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
21
Male patients
10
Female patients
14(<=60)+17(>=60)
Age range and number
Not available
PMID
Description
Long Non-Coding RNA NNT-AS1 Contributes to Cisplatin Resistance via miR-1236-3p/ATG7 Axis in Lung Cancer Cells
Tissue resource
lung cancer tissues and paracancerous non-tumorous tissues
lung cancer cell lines H1299
lung cancer cell lines H23
lung cancer cell lines H522
lung cancer cell lines A549
human bronchial epithelioid cell lines 16-HBE
Experiment
31
Institute
First Affiliated Hospital of Medical College of Zhejiang University
BeNa Culture Collection
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.