CircRNF111

ncRNA information

ncRNA name

CircRNF111

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-140-5p/E2F3

Cancer information

Cancer name

Breast Cancer

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Circ-RNF111 contributes to paclitaxel resistance in breast cancer by elevating E2F3 expression via miR-140-5p

Tissue resource

tissues from paclitaxel-resistant and paclitaxel-sensitive breast cancer patients

normal breast epithelial cell lines MCF-10A

breast cancer cell lines MCF-7

breast cancer cell lines MDA-MB-231

Experiment

None


Institute

China‚ÄźJapan Union Hospital of Jilin University

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian