Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
LOC645166
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
NF-ĪŗB/GATA3
Cancer name
Breast Cancer
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Adriamycin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Long noncoding RNA lnc-LOC645166 promotes adriamycin resistance via NF-ĪŗB/GATA3 axis in breast cancer
Tissue resource
breast cancer freshly-frozen biopsy samples
human Breast cancer cell lines MDA-MB-231
human Breast cancer cell lines MCF-7
Experiment
None
Institute
Dongguan People's Hospital of Southern Medical University
Tumor Cell Bank of the Chinese Academy of Medical Science
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.