CTRR-ncRNA

ncRNA information

ncRNA name

HOTAIR

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-217

Cancer information

Cancer name

Hepatocellular Carcinoma

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

Sorafenib

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

32462038

Description

LncRNA HOTAIR Contributes to Sorafenib Resistance through Suppressing miR-217 in Hepatic Carcinoma

Tissue resource

hepatocellular carcinoma cell lines Huh7

hepatocellular carcinoma cell lines Hep3B

hepatocellular carcinoma cell lines SNU-387

hepatocellular carcinoma cell lines SNU-449

Experiment

None

Institute

Country

Continent