CircUBAP2

ncRNA information

ncRNA name

CircUBAP2

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-506-3p/SEMA6D

Cancer information

Cancer name

Osteosarcoma

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

CircUBAP2 promotes SEMA6D expression to enhance the cisplatin resistance in osteosarcoma through sponging miR-506-3p

Tissue resource

tissues from cisplatin-responsive and cisplatin-resistant OS patients

osteosarcoma cell lines U2OS

osteosarcoma cell lines SaOS-2

Experiment

None


Institute

Yantai Affiliated Hospital of Binzhou Medical University

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian