SNHG1

ncRNA information

ncRNA name

SNHG1

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-381

Cancer information

Cancer name

Breast Cancer

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

LncRNA SNHG1 promotes tumor progression and cisplatin resistance through epigenetically silencing miR-381 in breast cancer

Tissue resource

human Luminal A and Luminal B Basal and HER2-positive breast cancer tissues

breast cancer cell lines MCF-7

breast cancer cell lines MDA-MB-231

normal epithelial cell lines MCF-10A

Experiment

None


Institute

Xijing Hospital, The Fourth Military Medical University

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian