MALAT1

ncRNA information

ncRNA name

MALAT1

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

PI3K/AKT/m-TOR Signal Pathway

Cancer information

Cancer name

Oral Squamous Cell Carcinoma

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

lncRNA MALAT1 Promotes EMT Process and Cisplatin Resistance of Oral Squamous Cell Carcinoma via PI3K/AKT/m-TOR Signal Pathway

Tissue resource

human ovarian squamous cell carcinoma cell lines CAL-27

human ovarian squamous cell carcinoma cell lines SCC-9

Experiment

None


Institute

Cell Bank of Peking Union Medical College

Country

China

Continent

Asia