Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-148a-3p
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
ATP7A
Cancer name
Breast Cancer
Cancer site
Breast
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Down
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
We also demonstrated miR-148a-3p overexpression in BRCA cells increased the sensitivity to cisplatin.
Tissue resource
breast cancer cell lines T47D
breast cancer cell lines MDA-MB-231
breast cancer cell lines T47D
breast cancer cell lines MDA-MB-231
Experiment
qRT-PCR,Western blot,Luciferase reporter assay
Institute
American Type Culture Collection
American Type Culture Collection
Country
USA
United States
Continent
North American
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.