LINC00152

ncRNA information

ncRNA name

LINC00152

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-613/YAP1

Cancer information

Cancer name

Retinoblastoma Cancer

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Carboplatin/Adriamycin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

20

Male patients

16

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

LINC00152 enhanced the aggressiveness of retinoblastoma and boosted carboplatin and adriamycin resistance by regulating YAP1 by sponging miR-613 in human retinoblastoma

Tissue resource

specimens of retinoblastoma tissue and normal retina tissues

human retinoblastoma cell lines Y79

human retinoblastoma cell lines Weri-RB-1

Experiment

36


Institute

Ningbo Eye Hospital

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian