Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa_circ_0007841
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
ABCG2
Cancer name
Multiple Myeloma
Cancer site
Multiple Myeloma
Treatment type
Chemotherapy
Drug
Doxorubicin
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Hsa_circ_0007841 promotes acquired chemotherapy resistance by upregulating ATP-binding cassette transporters G2 providing a novel molecular basis of chemotherapy in multiple myeloma cancer.
Tissue resource
multiple myeloma cell lines THP-1
multiple myeloma cell lines KM3
multiple myeloma cell lines U266
multiple myeloma cell lines RPMI-8226
multiple myeloma cell lines THP-1
multiple myeloma cell lines KM3
multiple myeloma cell lines U266
multiple myeloma cell lines RPMI-8226
Experiment
qRT-PCR,Western blot
Institute
American Type Culture Collection
ATCC cell bank
Country
USA
Continent
North American
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.