hsa_circ_0007841

ncRNA information

ncRNA name

hsa_circ_0007841

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

ABCG2

Cancer information

Cancer name

Multiple Myeloma

Cancer site

Multiple Myeloma

Treatment information

Treatment type

Chemotherapy

Drug

Doxorubicin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Hsa_circ_0007841 promotes acquired chemotherapy resistance by upregulating ATP-binding cassette transporters G2 providing a novel molecular basis of chemotherapy in multiple myeloma cancer.

Tissue resource

multiple myeloma cell lines THP-1

multiple myeloma cell lines KM3

multiple myeloma cell lines U266

multiple myeloma cell lines RPMI-8226

multiple myeloma cell lines THP-1

multiple myeloma cell lines KM3

multiple myeloma cell lines U266

multiple myeloma cell lines RPMI-8226

Experiment

qRT-PCR,Western blot


Institute

American Type Culture Collection

ATCC cell bank

Country

USA

Continent

North American