Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-199b-5p
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Rectal Cancer
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
5-Fluorouracil
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Up
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
42(<70)+40(>=70)
Age range and number
Not available
PMID
Description
MicroRNA-199b Downregulation Confers Resistance to 5-Fluorouracil Treatment
Tissue resource
consecutive specimens from patients with a histological diagnosis of LARC
human colorectal cancer cell lines SW480
human colorectal cancer cell lines HT-29
Experiment
82
Institute
University Hospital Fundación Jiménez Díaz
American Type Culture Collection
Country
Spain
United States
Continent
European
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.