hsa-miR-199b-5p

ncRNA information

ncRNA name

hsa-miR-199b-5p

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Rectal Cancer

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

5-Fluorouracil

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Up

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

42(<70)+40(>=70)

Age range and number

Not available

Research information

PMID

Description

MicroRNA-199b Downregulation Confers Resistance to 5-Fluorouracil Treatment

Tissue resource

consecutive specimens from patients with a histological diagnosis of LARC

human colorectal cancer cell lines SW480

human colorectal cancer cell lines HT-29

Experiment

82


Institute

University Hospital Fundación Jiménez Díaz

American Type Culture Collection

Country

Spain

United States

Continent

European

North Amercian