Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CRNDE
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-126-5p/ATAD2
Cancer name
Colorectal Carcinoma
Cancer site
qRT-PCR,Western blot
Treatment type
Chemotherapy
Drug
Paclitaxel
Impact of wild-type ncRNA on chemotherapy resistance
Up
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Up
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Long Non-Coding RNA CRNDE Promotes Colorectal Carcinoma Cell Progression and Paclitaxel Resistance by Regulating miR-126-5p/ATAD2 Axis
Tissue resource
colorectal cancer tissues and adjacent tissues and normal tissues
human normal cell lines NCM460
colorectal cancer cell lines Caco-2
colorectal cancer cell lines HT29
colorectal cancer cell lines HCT15
colorectal cancer cell lines SW480
colorectal cancer cell lines SW620
Experiment
None
Institute
Luoyang Central Hospital Affiliated to Zhengzhou University
Xiehe Cell Bank of the Chinese Academy of Medical Sciences
American Type Culture Collection
Country
China
China
United States
Continent
Asia
Asia
North Amercian
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.