CRNDE

ncRNA information

ncRNA name

CRNDE

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-126-5p/ATAD2

Cancer information

Cancer name

Colorectal Carcinoma

Cancer site

qRT-PCR,Western blot

Treatment information

Treatment type

Chemotherapy

Drug

Paclitaxel

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Up

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Long Non-Coding RNA CRNDE Promotes Colorectal Carcinoma Cell Progression and Paclitaxel Resistance by Regulating miR-126-5p/ATAD2 Axis

Tissue resource

colorectal cancer tissues and adjacent tissues and normal tissues

human normal cell lines NCM460

colorectal cancer cell lines Caco-2

colorectal cancer cell lines HT29

colorectal cancer cell lines HCT15

colorectal cancer cell lines SW480

colorectal cancer cell lines SW620

Experiment

None


Institute

Luoyang Central Hospital Affiliated to Zhengzhou University

Xiehe Cell Bank of the Chinese Academy of Medical Sciences

American Type Culture Collection

Country

China

China

United States

Continent

Asia

Asia

North Amercian