Exosome miR-500a-3p

ncRNA information

ncRNA name

Exosome miR-500a-3p

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

FBXW7

Cancer information

Cancer name

Gastric Cancer

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Exosomal MiR-500a-3p promotes cisplatin resistance and stemness via negatively regulating FBXW7 in gastric cancer

Tissue resource

blood sample from gastric cancer patients

gastric cancer cell lines MGC803

gastric cancer cell lines MKN45

Experiment

None


Institute

XuZhou Central Hospital

American Type Culture Collection

Country

China

United States

Continent

Asia

North Amercian