ncRNA name
CircFoxo3
Specific or universal ncRNAs
Specific ncRNAs
Class
Circular RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-199a-5p/ABCC1
Cancer name
Hepatocellular Carcinoma
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
None
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Up
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
circFoxo3 overexpression enhances HCC cell invasion and tumor growth through regulation of miR-199a-5p/ABCC1
Tissue resource
pairs of clinical tumors samples and matched normal tissues
human normal hepatocellular cells HL-7702
hepatocellular carcinoma cell lines SK-HEP-1
hepatocellular carcinoma cell lines HepG2
Experiment
None
Institute
Third Xiangya Hospital, Central South University
Chinese Academy of Sciences
Country
China
China
Continent
Asia
Asia