CircFoxo3

ncRNA information

ncRNA name

CircFoxo3

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-199a-5p/ABCC1

Cancer information

Cancer name

Hepatocellular Carcinoma

Cancer site

qRT-PCR,Western blot,Luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

None

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Up

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

circFoxo3 overexpression enhances HCC cell invasion and tumor growth through regulation of miR-199a-5p/ABCC1

Tissue resource

pairs of clinical tumors samples and matched normal tissues

human normal hepatocellular cells HL-7702

hepatocellular carcinoma cell lines SK-HEP-1

hepatocellular carcinoma cell lines HepG2

Experiment

None


Institute

Third Xiangya Hospital, Central South University

Chinese Academy of Sciences

Country

China

China

Continent

Asia

Asia