Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
MCF2L-AS1
Specific or universal ncRNAs
Specific ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Colorectal Cancer
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Oxaliplatin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
The MCF2L-AS1/miR-105/IL-1Ī² regulatory axis regulates the resistance of CRC cells to OXA treatment
Tissue resource
samples of tumor tissues were collected from patients with colorectal cancer
colorectal cancer cell lines HT-29
colorectal cancer cell lines LOVO
Experiment
None
Institute
The Second Affiliated Hospital of Wenzhou Medical University
the Type Culture Collection of the Chinese Academy of Sciences
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.