CDR1as

ncRNA information

ncRNA name

CDR1as

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-641/HOXA9

Cancer information

Cancer name

Non-Small Cell Lung Cancer

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

CircRNA CDR1as/miR-641/HOXA9 pathway regulated stemness contributes to cisplatin resistance in non-small cell lung cancer

Tissue resource

human non-small cell lung cancer cell lines A549

human non-small cell lung cancer cell lines H1299

human non-small cell lung cancer cell lines Calu6

human embryonic kidney cell lines 293T

human non-small cell lung cancer cisplatin-resistant cell lines A549/DDP

Experiment

None


Institute

American Type Culture Collection

Resistant Cancer Cell Line

Country

United States

Continent

North Amercian