Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
MALAT1
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
None
Biomarker application
Upstream regulatory factors
Not available
Downstream target
miR-362-3p/G3BP1
Cancer name
Renal Cell Carcinoma
Cancer site
qRT-PCR,Western blot,Luciferase assay
Treatment type
Chemotherapy
Drug
Sunitinib
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Down
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Depletion of lncRNA MALAT1 inhibited sunitinib resistance through regulating miR-362-3p-mediated G3BP1 in renal cell carcinoma
Tissue resource
pairs of human renal cell carcinoma tissues
human embryonic kidney cell lines 293T
hepatocellular carcinoma cell lines HK-2
hepatocellular carcinoma cell lines CAKI-2
hepatocellular carcinoma cell lines ACHN
hepatocellular carcinoma cell lines 769P
hepatocellular carcinoma cell lines 786O
Experiment
None
Institute
Yulin No.2 Hospital
Cell Bank of Type Culture Collection of Chinese Academy of Sciences
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.