Exosome Circ_UBE2D2

ncRNA information

ncRNA name

Exosome Circ_UBE2D2

Specific or universal ncRNAs

Specific ncRNAs

Class

Circular RNA

Biomarker

None

Biomarker application

Upstream regulatory factors

Not available

Downstream target

miR-200a-3p

Cancer information

Cancer name

Breast Cancer

Cancer site

qRT-PCR,Western blot,Dual-luciferase assay

Treatment information

Treatment type

Chemotherapy

Drug

Tamoxifen

Impact of wild-type ncRNA on chemotherapy resistance

Up

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Exosomes mediated transfer of circ_UBE2D2 reinforced tamoxifen resistance in breast cancer by binding to miR-200a-3p

Tissue resource

breast cancer tissues

human breast cancer cell lines MCF-7

human breast cancer cell lines T47D

human breast cancer cell lines 293T

Experiment

None


Institute

Shenzhen University General Hospital

Shanghai Academy of life Science

Country

China

China

Continent

Asia

Asia